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Medicines that inhibit CYP2D6 activity, which include paroxetine and quinidine, may well bring about reduced clearance of oxycodone which could lead on to a rise in oxycodone plasma concentrations. Concurrent administration of quinidine resulted in an increase in oxycodone Cmax by eleven%, AUC by 13%, and t½ elim.Ritonavir or lopinavir/ritonavir s